C1q/ TNF ‐related peptide 8 ( CTRP 8) promotes temozolomide resistance in human glioblastoma

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ATP7B expression in human glioblastoma is related to temozolomide resistance

Glioblastoma multiforme (GBM) is one of the most aggressive types of brain malignancy, with resistance to chemotherapy being a primary treatment obstacle. ATPase copper transporting β (ATP7B) is involved in multidrug resistance; however, its expression in GBM remains to be evaluated. In the present study, GBM specimens from 79 patients who underwent gross total tumor removal followed by concomi...

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Association of serum C1q/TNF-related protein-3 (CTRP-3) in patients with coronary artery disease

BACKGROUND Recent studies have demonstrated that complement C1q tumor necrosis factor related proteins (CTRPs) have diverse biological influences on the cardiovascular system. CTRP 3 is a member of the CTRP superfamily, which may play a pivotal role in the pathogenesis of coronary artery disease (CAD). Here, we investigated whether serum levels of CTRP 3 are associated with the prevalence and t...

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THE EFFECTS OF AEROBIC, RESISTANCE, AND COMBINED EXERCISE ON C1Q/TNF-RELATED PROTEIN-5 (CTRP-5) LEVELS AND GLYCEMIC PARAMETERS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Background: It has been shown that C1q TNF-related protein 5 (CTRP5) is a novel adipokine and important molecule related to metabolism regulation. This study aims to assess the effectiveness of different training protocols on improving serum levels of CTRP5, fasting blood glucose, insulin, Insulin resistance in patients with T2DM. Methods: Sixty men with T2DM (mean age [X̅±SD]=51.45±4.26 years)...

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Circulating Levels of C1q/TNF-Related Protein-12 (CTRP-12) in Patients with Type 2 Diabetes: A Case-control Study

Background: The C1q complement/TNF-related protein (CTRP) superfamily is a newly diagnosed adipokine with anti-inflammatory, insulin sensitivity, and glucose lowering effects. This study aimed to assess the plasma circulating levels of CTRP12 in type 2 diabetic (T2D) patients and healthy subjects. Methods: In this case-control study, plasma concentration of CT...

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Effects of a Combined Aerobic and Resistance Exercise Program on C1q/TNF-Related Protein-3 (CTRP-3) and CTRP-5 Levels

OBJECTIVE To examine the effect of a combined exercise program on C1q/tumor necrosis factor-related protein (CTRP) 3 and CTRP-5 levels and novel adiponectin paralogs suggested to be links between metabolism and inflammation and to evaluate sex differences and association with cardiometabolic risk factors in humans with use of a newly developed ELISA. RESEARCH DESIGN AND METHODS This cross-sec...

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ژورنال

عنوان ژورنال: Molecular Oncology

سال: 2018

ISSN: 1574-7891,1878-0261

DOI: 10.1002/1878-0261.12349